Who We Are

At Syndax, we are advancing the next generation of targeted treatments to realize a future in which people with cancer live longer and better than ever before.

We are a clinical stage oncology innovator developing first-in-class therapies for acute leukemias and chronic graft-versus-host disease. Our team is committed to adhering to scientific excellence and dedicated to serving the patient community by delivering therapeutics that provide meaningful and differentiated clinical results and address urgent unmet need.

Treatment Pipeline

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Revumenib is a potent, selective, small molecule inhibitor of the menin-KMT2A interaction being developed for the treatment of KMT2A-rearranged acute leukemias, including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and NPM1-mutated AML.

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Axatilimab is an investigational monoclonal antibody that targets colony stimulating factor-1 receptor, or CSF-1R, a cell surface protein thought to control the survival and function of monocytes and macrophages, being developed for chronic graft-versus-host disease and idiopathic pulmonary fibrosis.

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